Yuwei HU
Research Scientist
Tel: +65 6319 4807
Email: ywhu@imre.a-star.edu.sg
Research Scientist, NanoBio Lab, Singapore, 2018‐present
Research Scientist, Institute of Bioengineering and Nanotechnology, Singapore, 2018
Research Fellow, National University of Singapore, 2016‐2017
Post‐Doctoral Researcher, The Hebrew University of Jerusalem, 2013‐ 2016
Ph.D. in Analytical Chemistry, Jilin University, China, 2013
M.Sc. in Analytical Chemistry, Qingdao University of Science & Technology, China, 2010
B.Sc. in Chemistry, Qingdao University of Science & Technology, China, 2007
Publications
Y. Hu and J. Y. Ying, “A Strong Acid-Induced DNA Hydrogel Based on pH-Reconfigurable A-Motif Duplex,” Small, DOI: 10.1002/smll.202205909.
Y. Hu and J. Y. Ying, “Reconfigurable A-Motif, i-Motif and Triplex Nucleic Acids for Smart pH-Responsive DNA Hydrogels,” Mater. Today, DOI: 10.1016/j.mattod.2022.12.003.
Y. Hu, S. Gao, H. Lu, J.-Y. Ying, “Acid-Resistant and Physiological pH-Responsive DNA Hydrogel Composed of A-Motif and i-Motif toward Oral Insulin Delivery”, J. Am. Chem. Soc. 2022, 144, 5461−5470
B. Xu, X. Han, Y. Hu, Y. Luo, C.-H. Chen, Z. Chen, P. Shi, “A Remotely Controlled Transformable Soft Robot Based on Engineered Cardiac Tissue Construct”, Small, 2019, 1900006
S. Guo, W. N. Lin, Y. Hu, G. Sun, D.-T. Phan, C.-H. Chen, “Ultrahigh-throughput droplet microfluidic device for single-cell miRNA detection with isothermal amplification”, Lab Chip, 2018, 18, 1914–1920
Y. Hu, A. Cecconello, A. Idili, F. Ricci, I. Willner, “Triplex DNA Nanostructures: From Basic Properties to Applications,” Angew. Chem. Int. Ed., 56 (2017) 15210‐15233
J. S. Kahn, Y. Hu, I. Willner, “Stimuli‐Responsive DNA‐Based Hydrogels: From Basic Principles to Applications,” Acc. Chem. Res., 50 (2017) 680‐690
Y. Hu, J. S. Kahn, W. Guo, F. Huang, M. Fadeev, D. Harries, I. Willner, “Reversible Modulation of DNA‐Based Hydrogel Shapes by Internal Stress Interactions,” J. Am. Chem. Soc., 138 (2016) 16112‐16119
Y. Hu, J. Ren, C.‐H. Lu, I. Willner, “Programmed pH‐Driven Reversible Association and Dissociation of Inter‐Connected Circular DNA Dimer Nanostructures,” Nano Lett., 16 (2016) 4590‐4594
Y. Hu, W. Guo, J. S. Kahn, M. A. Aleman‐Garcia, I. Willner, “A Shape Memory DNA‐Based Hydrogel Exhibiting Two Internal Memories,” Angew. Chem. Int. Ed., 55 (2016) 4210‐4214
X. Yu, Y. Hu, J. S. Kahn, A. Cecconello, I. Willner, “Orthogonal Dual Triggered Shape‐Memory DNABased Hydrogels,” Chem.‐Eur. J., 22 (2016) 14504‐14507
M. A. Aleman Garcia, Y. Hu, I. Willner, “Switchable Supramolecular Catalysis using DNA‐templated Scaffolds,” Chem. Commun., 52 (2016) 2153‐2156
Y. Hu, C.‐H. Lu, W. Guo, M. A. Aleman‐Garcia, J. Ren, I. Willner, “A Shape‐Memory Acrylamide/DNA Hydrogel Exhibiting Switchable Dual pH Responsiveness,” Adv. Funct. Mater., 25 (2015) 6867‐6874
J. Ren, Y. Hu, C.‐H. Lu, W. Guo, F. Ricci, I. Willner, “pH Responsive and Switchable Triplex‐Based DNA Hydrogels,” Chem. Sci., 6 (2015) 4190‐4195
C.‐H. Lu, W. Guo, Y. Hu, X.‐J. Qi, I. Willner, “Multi‐Triggered Shape‐Memory Acrylamide–DNA Hydrogels,” J. Am. Chem. Soc., 137 (2015) 15723‐15731
Y. Hu, F. Wang, C.‐H. Lu, J. Girsh, E. Golub, I. Willner, “Switchable Enzyme/DNAzyme Cascades by the Reconfiguration of DNA Nanostructures,” Chem.‐Eur. J., 20 (2014) 16203‐16209
W. Zhang, F. Li, Y. Hu, S. Gan, D. Han, Q. Zhang, L. Niu, “Perylene Derivative‐Bridged Au–Graphene Nanohybrid for Label‐Free HpDNA Biosensor,” J. Mater. Chem. B, 2 (2014) 3142‐3148
N. Zhang, X. Lv, W. Ma, Y. Hu, F. Li, D. Han, L. Niu, “Direct Electron Transfer of Cytochrome C at Mono‐dispersed and Negatively Charged Perylene–Graphene Matrix,” Talanta, 107 (2013) 195‐202
Y. Hu, T. Yang, Q. Li, Q. Guan, K. Jiao, “Conjugated Self‐Doped Polyaniline–DNA Hybrid as Trigger for Highly Sensitive Reagentless and Electrochemical Self‐Signal Amplifying DNA Hybridization Sensing,” Analyst, 138 (2013) 1067‐1074
Y. Hu, F. Li, D. Han, T. Wu, Q. Zhang, L. Niu, Y. Bao, “Simple and Label‐Free Electrochemical Assay for Signal‐On DNA Hybridization Directly at Undecorated Graphene Oxide,” Anal. Chim. Acta, 753 (2012) 82‐89
L. Fan, Y. Hu, X. Wang, L. Zhang, F. Li, D. Han, Z. Li, Q. Zhang, Z. Wang, L. Niu, “Fluorescence Resonance Energy Transfer Quenching at the Surface of Graphene Quantum Dots for Ultrasensitive Detection of TNT, Talanta, 101 (2012) 192‐197
Y. Hu, K. Wang, Q. Zhang, F. Li, T. Wu, L. Niu, “Decorated Graphene Sheets for Label‐Free DNA Impedance Biosensing,” Biomaterials, 33 (2012) 1097‐1106
Y. Hu, D. Han, Q. Zhang, T. Wu, F. Li, L. Niu, “Perylene Ligand Wrapping G‐Quadruplex DNA for Label‐Free Fluorescence Potassium Recognition,” Biosen. Bioelectron., 38 (2012) 396‐401
Y. Hu, F. Li, X. Bai, D. Li, S. Hua, K. Wang, L. Niu, “Label‐Free Electrochemical Impedance Sensing of DNA Hybridization Based on Functionalized Graphene Sheets,” Chem. Commun., 47 (2011) 1743‐1745
Y. Hu, S. Hua, F. Li, Y. Jiang, X. Bai, D. Li, L. Niu, “Green Synthesized Gold Nanoparticles Decorated Graphene Sheets for Label‐Free Electrochemical Impedance DNA Hybridization Biosensing,” Biosen. Bioelectron., 26 (2011) 4355‐4361
J. Chai, F. Li, Y. Hu, Q. Zhang, D. Han, L. Niu, “Hollow Flower‐Like AuPd Alloy Nanoparticles: One Step Synthesis, Self‐Assembly on Ionic Liquid‐functionalized Graphene and Electrooxidation of Formic Acid,” J. Mater. Chem., 21 (2011) 7922‐17929
T. Yang, Y. Hu, W. Li, K. Jiao, “Single Stranded DNA‐Guided Electropolymerization of Polythionine Nanostrip to the Sensing of H2O2,” Colloid. Surface. B, 83 (2011) 179‐182
Y. Hu, T. Yang, X. Wang, K. Jiao, “Highly Sensitive Indicator‐Free Impedance Sensing of DNA Hybridization Based on Poly(m‐aminobenzenesulfonic acid)/TiO2 Nanosheet Membranes with Pulse Potentiostatic Method Preparation,” Chem.‐ Eur. J., 16 (2010) 1992‐1999
X. Zhang, K. Jiao, S. Liu, Y. Hu, “Readily Reusable Electrochemical DNA Hybridization Biosensor Based on the Interaction of DNA with Single‐Walled Carbon Nanotubes,” Anal. Chem., 81 (2009) 6006‐6012
X. Zhang, S. Liu, K. Jiao, Y. Hu, “Fabrication, Characterization, and Application of Sandwich‐Type Electrode Based on Single‐Walled Carbon Nanotubes and Room Temperature Ionic Liquid,” Electroanal., 20 (2008) 1909‐1916